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Drug Discovery & Development  
 
NIST Trumps the Clumps: Making Biologic Drugs Safer
Scientists at the National Institute of Standards and Technology (NIST) have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals. ...continue

'Statins' May Improve Survival in Kidney Transplant Recipients
For patients receiving kidney transplants, treatment with cholesterol-lowering "statin" drugs may lead to longer survival, reports a study in the November 2008 Journal of the American Society of Nephrology. ...continue

Protein Able to Stimulate Production of T-cells
A team of Canadian and Finnish scientists has identified a protein able to stimulate the production of T-cells, the white blood cells involved in the recognition and the elimination of infectious agents. ...continue

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Nikon BioStationCT Cell Culture Observation
The BioStation CT allows imaging experiments to be conducted without removing the cells from the incubator. Get a "bird's eye" color macro view from above. ... continue
 

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White Papers
Impact of Microplate Choice on HTRF Assay Performance
Homogeneous Time-Resolved Fluorescence (HTRF) assays, critical tools for the study of molecular interactions, can be impacted by peripheral components, such as microplates. This study examines the factors of plate color and well geometry. ...continue

Quantitative Cleaning Validations using a Universal HPLC Detector
HPLC with charged aerosol detection (CAD) provides a more accurate detection tool to quantitate the drug substance. ...continue

Improving Productivity in the Determination of Parameters for Early in vitro ADME
The authors demonstrate high throughput quantification of drug compounds, which increases productivity in determining parameters for early in vitro ADME studies. ...continue

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Informing Personalized Medicine
Drug Discovery & Development July 2008 CoverPersonalized medicine—the use of genetic and genomic information to predict, prevent, and treat disease—is receiving widespread attention from both the public and the scientific community. To fulfill the promise, what must be done to bridge the gap between old-school and new-school drug development?
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    Drug Discovery

    Drug Development

    Genomics & Proteomics

    Policy & Projections

    Technology Advances

Atomic Force Microscope
Agilent Technologies Inc. offers the Agilent 5600LS, a high-resolution atomic force microscope that uses a fully addressable 200mm x 200mm stage to image large samples in air or smaller samples in liquid. ...continue

Imaging Data Delivery
NanoImaging Services, Inc., offers NanoImaging Data Browser, a data delivery service that provides its customers access to the massive data sets generated by image-based structural investigations. ...continue

Transmission Electron Microscope
FEI Company offers a high-throughput, cryo transmission electron microscope (TEM) that combines high-throughput sample handling with state-of-the-art electron optics. ...continue

Slide Scanners
Biomedical Photometrics slide scannerBiomedical Photometrics Inc., introduces panoramic confocal fluorescence and brightfield slide scanners, the TISSUEscope 4000, for the genomics and general microscopy markets. ...continue

Fluorescence Stereomicroscopy
The Leica M205 FA and M165 FCThe Leica M205 FA and M165 FC stereomicroscopes are Leica Microsystems‘ latest addition to its M series for fluorescence applications in developmental, molecular, and cellular biology. ...continue

Diagnosing Tuberculosis Using a Microscope
Carl Zeiss Microscope for TB diagnosisTogether with the Foundation for Innovative New Diagnostics (FIND), Carl Zeiss has developed a special microscope to improve the diagnosis of tuberculosis. ...continue

Live Cell Monitoring of cAMP Kinetics
Promega Corporation offers GloSensor Technology cell-based biosensor technology for real-time monitoring of cAMP kinetics. ...continue

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Science, Business, and Controversy Are Keynotes
DDT 2008 BostonThe keynote line up for the 13th Annual Drug Discovery & Development of Innovative Therapeutics World Congress in Boston includes scientific, business, and controversial topics. ...continue

Cancer Therapies Highlight Program
The Focus on Cancer track at the Drug Discovery & Development of Innovative Therapeutics Conference and Exhibition will feature presentations on therapies for Hematology, Lung Cancer, Blood Borne Cancers, and Clinical Biomarkers. ...continue

Evaluate New Technologies at DDT 2008
DDT2008 Exhibit HallThe Drug Discovery & Development of Innovative Therapeutics exhibit hall offers a comprehensive display of drug discovery technology, including technologies used from drug discovery to clinic. ...continue

The Race to the $1000 Genome: Sprinting Toward the Finish Line
The question of when it will be possible to sequence a human genome is being replaced by concerns whether the average consumer will choose to have his or her genome sequenced. ...continue

Delivering Knowledge Through Effectively Managed Screening Data
All too often, drug discovery organizations rely on ‘experts’ to make decisions while in many cases the data is readily available for anyone to use—if it is viewed and accessed in the right way. ...continue

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