Drug Discovery & Development provides readers with an inside look at how leading pharmaceutical and biotechnology researchers are applying the latest discovery tools and development techniques. In every issue, readers view:
- Feature articles cover the full continuum of drug discovery and development, including genomics and proteomics reporting on research, applications, technologies, and strategies to accelerate the pace and productivity of drug research and development.
- Technology Focus highlights the latest news, products, services, and applications for specific discovery, development, genomics, and proteomics technologies.
- Industry Issues features focus on strategies and topics that impact pharma and biotech business both inside and outside the lab including two monthly columns.
- Technology Advances previews new technology trends.
- Policy & Projections analyzes current legislative and regulatory issues in Congress, the FDA, the courts, and other governing bodies.
Preview the 2008 Editorial Calendar or review upcoming topics:
September, 2008 | October, 2008 | November, 2008
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September, 2008 Issue
Cover Story
Peptide-based Therapeutics
Oncology drug discovery programs often follow a multi-prong approach, utilizing a variety of new technologies including peptide-based therapeutics. What are the challenges in the discovery, development and manufacture of peptide-based therapeutics?
Instrumentation
Technology Focus: Spectroscopy/spectrometry
The latest technologies and tools for spectroscopy and spectrometry are reported.
Assay Development
Sample Prep for PCR
Senior Editor James Netterwald will discuss the challenges in obtaining clinical samples free of PCR inhibitors.
Technology Focus: PCR Technologies
The latest technologies and tools for PCR are reported. Submission deadline: August 2.
Cell-based Technologies
Special Series
Cell Biology Study: Microscopy and Labeling
What cells do you study? In the continuing series, life science researchers explain how they study cells: the imaging and labeling technologies used, as well as the types of microscopes and software.
Genomics and Proteomics
Transmembrane Protein Isolation
Senior Editor James Netterwald will discuss the latest methods for extraction, separation, and analysis of this difficult-to-isolate protein family.
miRNA cloning
To identify new small RNA molecules, a more complicated protocol is required that involves amplifying the amount of RNA by cloning before identification using sequencing techniques.
Technology Focus: Gene Expression
The latest technologies and tools for gene expression are reported. Submission deadline: August 2.
Chemistries
Technology Focus: Proteins and Peptides
The latest technologies and tools for proteins and peptides are reported. Submission deadline: August 2.
Drug Development
Pediatric Vaccines
From childhood illnesses to HPV, the pediatric vaccine market is changing. The challenges of developing pediatric vaccines is examined.
Industry Issues
Politics and Pharma/Biotech
As the presidential election heads to the finish line, where do the candidates stand on key issues impacting science, research, and the pharmaceutical industry?
Departments
Technology Advances: in silico Analysis
Contributing Editor Mike May will discuss advances in in silico analysis.
Policy & Projections
Contributing Editor Ted Agres will examine the growing number of consortiums and collaborations in the industry.
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October, 2008 Issue
Cover Story
The Evolution of R&D:
Will Virtual Man Become a Reality?
In the not-so-distant future, research and development processes will look very different, and will require a different set of skills, tools, and reward structure for researchers. If research is virtualized, scientific and technological advances could render the current four-phase development process obsolete.
Instrumentation
Ion Exchange Chromatography
This article will address the applications, challenges, and limitations of this powerful chromatographic method.
Technology Focus: Chromatography Columns
The latest chromatography columns are reported. Submission deadline: September 2, 2008
Assay Development
Immunochemistry in Molecular Diagnostics
Antibody-based detection systems – the bread and butter of the immunoassay – will be discussed in the context of a Molecular Diagnostic Testing format used in the clinical setting to diagnose disease.
Cell-based Technologies
Cell Biology Study: Research Challenges
Research labs need adequate funding levels and sources to succeed. How do funding issues impact research projects? Is there pressure to commercialize findings?
Technology Focus: Stem Cells
The latest technologies and tools for stem cell research are reported. Submission deadline: September 2.
Genomics and Proteomics
Western Blotting
Are researchers still using this technique? What are the applications? Recent advances in this technology, along with compatible techniques, will be explored.
Technology Focus: Proteomics
The latest technologies and tools for proteomics research are reported. Submission deadline: September 2.
Drug Safety
Early ADME Studies with Radiolabeling Techniques
This article will discuss radiolabeling analysis methods and technologies in early ADME testing, including use of specific activity determination and analytical HPLC to determine precise measurements of compound identity, purity, and activity.
Technology Focus: ADME-Tox Tools and Services
The latest ADME-Tox tools and services are reported. Submission deadline: September 2.
Automation
High Throughput Parallel Screening
Industry Issues
Outsourcing
When you cannot “do it yourself” outsourcing is the option. But, what type of outsourcing service do you choose? Academic, for-profit, or non-profit?
Departments
Technology Advances: in vitro Analysis
Policy and Projections: Current legislative and regulatory issues
Technology Innovations
Recent Product Introductions
News
Life Science Update
Drug Pipeline Progress
Partnerships and Collaborations
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November 2008 Editorial Content
Cover Story
Drug Discovery & Development: The Next Decade
As the magazine celebrates 10 years of publishing, pharma and biotech leaders, as well as industry suppliers look ahead to the technologies, science, regulatory, economic, and societal impacts on drug discovery and development.
Instrumentation
Technology Focus:
2D Gel Electrophoresis
Imaging Systems
The latest 2D gel and imaging systems are reported. Submission deadline: October 2, 2008
Assay Development
Improved Microplate Luminescence Results
No matter the light intensity preference or overall assay purpose, careful attention to the certain factors can boost efficiency and greatly improve luminescence assay results.
Cell-based Technologies
Special Series
Cell Biology Study: Discovery Trends
Drug researchers report on key trends in discovery research: large molecule vs. small molecule, faster or slower research, and more.
Cell Culture and Cell Adhesion
The principles of cell adhesion, the basic technologies used to modify surfaces for improved adhesion, and how various surface compositions can affect cell growth will be discussed.
Genomics and Proteomics
PCR for Molecular Diagnostics
With PCR tools, researchers can copy a single, small, specific area of DNA numerous times. The latest technologies and methodologies will be examined.
Technology Focus: Microarrays
The latest technologies and tools for microarrays are reported. Submission deadline: October 2.
Drug Safety
Pharmacogenetics
An individual patient’s genetic makeup will determine their response to a drug. Senior Editor James Netterwald will explore current research practices, technologies and methodologies.
Drug Delivery
Nanotechnology for Drug Delivery
Contributing Editor Alan Dove will explore nanotechnology approaches to drug delivery to improve the bioavailability of a drug.
Departments
Technology Advances
Contributing Editor Mike May will discuss advances in lead optimization.
Policy & Projections
Contributing Editor Ted Agres will examine current legislative and regulatory issues.
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