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Drug Discovery & Development  
 
GFP Researchers Awarded Nobel Prizes
This year's Nobel Prize in Chemistry rewards the initial discovery of green fluorescent protein and a series of important developments, which have led to its use as a tagging tool in bioscience. ...continue

Molecule Coordinates Movement of Cells
Scientists at Rockefeller University have demonstrated that a molecule, ACF7, helps regulate and power cellular movement from the inside, findings that could have implications for understanding how cancer cells metastasize. ...continue

Structure of Adenosine Receptor Defined
Scientists from The Scripps Research Institute have determined the structure of an adenosine receptor that plays a critical role in a number of important physiological processes including pain, breathing, and heart function. ...continue

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Nikon BioStationCT Cell Culture Observation
The BioStation CT allows imaging experiments to be conducted without removing the cells from the incubator. Get a "bird's eye" color macro view from above. ... continue
 

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White Papers
Peristaltic versus Piston Pumps for Biopharmaceutical Dispensing
Peristaltic versus Piston Pumps for Biopharmaceutical Dispensing, Watson-Warlow Flexicon Peristaltic pump design innovations have been developed to dispense injectable drugs, reducing cost of bringing new drugs to market. The pumps can can the way products are mass-produced. Read more of this white paper. ...continue

Impact of Microplate Choice on HTRF Assay Performance
Homogeneous Time-Resolved Fluorescence (HTRF) assays, critical tools for the study of molecular interactions, can be impacted by peripheral components, such as microplates. This study examines the factors of plate color and well geometry. ...continue

Quantitative Cleaning Validations using a Universal HPLC Detector
HPLC with charged aerosol detection (CAD) provides a more accurate detection tool to quantitate the drug substance. ...continue

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Brave New R&D World
Drug Discovery and Development October 2008Is “virtual man” science fiction or a scientific necessity for drug development? Bioinformatics, systems biology and other disciplines may open the door to shorter research cycles and, ultimately, a digital view of how the human body and drugs interact. ...continue

    Drug Discovery

    Drug Development

    Genomics & Proteomics

    Policy & Projections

    Technology Advances

Technology in Action: The Hunt for miRNA
The discovery of microRNA opened new doors for drug research. Now, tools are helping researchers study even more regulatory RNA molecules. ...continue

Managing LC Variables
Developers of new methods for liquid chromatography battle a range of variables: buffer concentration, flow rate, reagents, and more. ...continue

Waters Unveils Mass Spec, Separations Science Tools
Waters Xevo TQ MS Mass SpecWaters Corporation unveiled several new mass spectrometry innovations at the 56th American Society for Mass Spectrometry Conference including the Waters XevoTM TQ MS System. ...continue

Desktop Drugs
in silico predictions establish a beachhead in the war on cancer. ...continue

It's Tox Season
ADME-Tox gets a new face as more efficient systems are brought on board and collaborations with regulators ensue. ...continue

The Blockbuster Alternative
Adaptive trial conceptInformation-based medicine maps a model for targeted drug therapies using biomarkers, modeling and simulation, and adaptive clinical trials. ...continue

Modeling and Simulation Software
Accelrys, Inc., San Diego, Calif., announced the release of  Discovery Studio 2.0, a modeling and simulation software environment for drug discovery. ...continue

More Technology Spotlight


 

Immnotherapy Welcomes TLR7
Researchers attempting to establish immunotherapies have been challenged when dosing with TLR agonists. With a better understanding of how to optimize the schedule of administering TLR7 agonists in different disease states, they may be able to sculpt the immune response appropriately for different diseases. ...continue

Lilly to Acquire ImClone Systems
Eli Lilly and Company and ImClone Systems Inc. announced a definitive merger agreement under which Lilly will acquire ImClone through an all cash tender offer of $70.00 per share, or approximately $6.5 billion. ...continue

Emerging Trends in Cell Biology Research 2008
Funding levelsDrug Discovery & Development and Bioscience Technology magazines asked drug and life science researchers about current practices, trends, and research challenges in cell biology. What are the top technical challenges? Are funding levels adequate? ...continue

in vitro Analysis of Neurons
Promega GloSensor cAMP Reagent 2Tracking normal development and disease pathways in the nervous system creates challenges at least as complex as the network of 100 billion neurons in the human brain. New products help researchers unravel what neurons do. ...continue

Down on the Pharm
Policy and Projections - PharmingResearch into producing inexpensive, plant-based therapeutic proteins, antibodies, and vaccines is making quiet progress, yet commercialization remains to be seen due to environmental opposition, high R&D costs, and regulatory and industry uncertainty. ...continue

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Academic SourcebookA report on the state of science in universities and colleges, from Advantage Business Media’s Science Group
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