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Lantus Investigated By FDA
The Food and Drug Administration is reviewing data on the safety of Lantus, a synthetic insulin, after a recent study raised the possibility the once-a-day insulin slightly increases risk of cancer.
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J&J Buys Stake In Elan
Johnson & Johnson announced it will take an 18.4 percent stake Ireland-based drug developer Elan Corp. with a $1 billion investment. The news sent Elan's shares soaring in premarket activity.
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Black Box Warning for Chantix and Zyban
The FDA is requiring manufacturers to put a Boxed Warning on the prescribing information for the smoking cessation drugs Chantix (varenicline) and Zyban (bupropion). The warning will highlight the risk of serious mental health events including changes in behavior, depressed mood, hostility, and suicidal thoughts.
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Computer Program Tackles Antibody Aggregation
A new computer model developed at MIT can help solve a problem that has plagued drug companies trying to develop promising new treatments made of antibodies: Such drugs have a relatively short shelf life because they tend to clump together, rendering them ineffective.
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Federal Probe Finds Problems With Chelation Study
A federal investigation has found that heart attack survivors enrolled in a study of a controversial alternative medicine treatment were not told enough about potential dangers from the drug being tested, including death.
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More Headlines
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Scanning Microplate Reader
 Biochrom Ltd. has released the latest product in their Anthos range of high-performance microplate instruments. The compact Zenyth 200 is a high-performance scanning microplate reader with the added benefit of a built-in UV/Vis spectrophotometer.
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Liquid Handling Workstation
 Hamilton Robotics announced a successful collaboration with Madison, Wisconsin-based Promega Corporation to automate the CellTiter-Glo luminescent cell viability assay on Hamilton’s MICROLAB STAR liquid handling workstation.
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TLC Plate Reader
 Syngene introduces its ChromaScan range of cost-effective automated TLC plate readers for rapid, accurate documentation and analysis of non-radioactive TLC (thin-layer chromatography) plates.
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Cell Culture Supplement
Recent studies using both classical media and the leading commercial serum-free hybridoma media formulations proved that InVitria’s cell culture supplements optimized cell growth and productivity of hybridoma cells.
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Filter Plate
 Millipore Corporation, a provider of technologies, tools and services for the bioscience research and biopharmaceutical manufacturing industry, has added the Millicell 1 μm, 24-well filter plate as part of its “Stem Cell Tested” initiative.
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More New Technologies
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The Race for the Lead
 Structure-based in silico modeling has quietly become the leading approach used in compound screening and lead optimization by pharmaceutical companies and contract research organizations.
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 Policy & Projections
The Hunt for Personalization
 Government research agencies, academic institutions, and large (and small) pharmaceutical, biotech, sequencing, and diagnostic companies continue to explore links between genetic variability and common diseases with the goal of developing targeted drugs and therapies.
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Technology Advances
Adding Choice to Chromatography
 Today’s researchers want more options from chromatography. So when PerkinElmer started to develop its new Flexar liquid chromatography (LC) platform, Alessandro Baldi, PhD, the company’s chromatography marketing manager, says that they focused on one thing: choice.
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Spectrometry Support Services
Applied Biosystems is offering compliance, remote monitoring, and maintenance services through its Global Services organization to better support its mass spectrometry customers.
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Microarray Scanners
 Roche NimbleGen introduces a new high-resolution scanning instrument, the NimbleGen MS 200 Microarray Scanner. The MS 200 is the first scanner optimized to reveal the full potential and capture the complete picture from all NimbleGen DNA microarrays.
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Recombinant Protein Expression System
Ajinomoto AminoScience, LLC, announced the launch of Corynex Recombinant Protein Expression System, a streamlined, more efficient process to express proteins. The breakthrough, patented system overcomes traditional microbial expression difficulties by secreting correctly folded, active proteins directly into the growth media.
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Biomarker Assay
NextGen Sciences and Expression Pathology, Inc. have developed a protein biomarker assay methodology that provides, for the first time, rapid, reproducible, quantitative measurement of protein expression in formalin fixed paraffin embedded (FFPE) tissue samples.
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Dissolution Testing
Microtest Laboratories is adding dissolution testing to its current suite of analytical testing and stability services. Dissolution is a compendial method used to measure a drug’s rate of release from its dosage form.
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2-D Protein Extraction Buffer
 GE Healthcare has introduced 2-D Protein Extraction Buffer, a series of six buffers for efficient and reproducible extraction of high quality protein lysates with high yield.
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Protein System
 At the recent BioProcess International (BPI) congress in Dusseldorf, Lab901 unveiled its new ScreenTape P200 product for rapid SDS-PAGE and analysis.
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More Technology Spotlight
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CenterWatch Releases Studies on Physician Referrals
CenterWatch presented never-before released results from two annual surveys aimed at better understanding physician referrals to clinical trials and study volunteer experiences at DIA’s 45th Annual Meeting in San Diego, California.
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Sigma Adds 2300 Antibodies to Prestige Antibodies Line
Sigma-Aldrich announced the release of over 2,300 antibody additions to its Prestige Antibodies powered by Atlas Antibodies product line, bringing the total number of highly validated antibodies to over 6,100.
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Eli Lilly Launches Drug Discovery Program
Eli Lilly and Company will be engaging researchers from around the world in a new and unique drug discovery initiative for Alzheimer's disease, cancer, diabetes, osteoporosis.
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Gov't Spends $2.5B In Failed Search for Alternative Meds
Ten years ago the government set out to test herbal and other alternative health remedies to find the ones that work. After spending $2.5 billion, the disappointing answer seems to be that almost none of them do.
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Women Underrepresented in Cancer Research
Women continue to be under-enrolled in cancer clinical trials, according to a new review, published in the July 15, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society. The study's results suggest that greater efforts are needed to ensure that oncologists know the true effects of treatments and medical procedures in female patients.
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More Recommended Reading
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 Helping Hands for Formulation
The goals: Get the drug into the clinic faster. Get the drug on the market faster. Contract formulation services can provide the needed "helping hands" to speed the drug development process. continue
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 A report on the state of science in universities and colleges, from Advantage Business Media’s Science Group Read now …
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Millipore Corporation released their AllostericProfiler service for use by researchers developing new drugs using G-protein coupled receptors (GPCRs). Increasingly, drug makers are focusing on novel allosteric GPCR sites to open up new chemical spaces. Allosteric GPCR binding sites modulate native ligand binding sites and are potentially more specific.
Wide-field Raman chemical imaging can deliver ingredient-specific particle size distributions for inhalation drugs.
Agilent Technologies Inc. has introduced the Agilent 1290 Infinity Liquid Chromatography System, designed to deliver significantly greater power, speed, and sensitivity to the high-end Ultra High Performance Liquid Chromatography (UHPLC) market.
Celsis International plc launched the Celsis ReACT, the first RNA-based assay for detecting objectionable organisms without the need for expensive equipment or specialized training.
Newer formulations and alternative technologies can help overcome the drawbacks of Coomassie protein visualization in PAGE gels.
